Innovative natural buffer agent

Energy concentration, a necessity, with consequences in the rumen

The accumulation of acids in the rumen from the fermentation of large quantities of carbohydrates (starches or sugars) leads to a decrease in ruminal pH that may lead to ruminal sub acidosis or nutritional acidosis.​

Nutritional acidosis is often found in dairy cows with a high genetic potential at the start of lactation. The energy requirements of highly productive dairy cows mean they need to ingest very large quantities of organic material that are rapidly fermented in the rumen.​

Subclinical acidosis mainly occurs with diets that are rich in cereals or based on maize silage, but can also occur while grazing on young grass with high sugar levels.​


TIMAB Magnesium innovates in the management of high energetic diet.


​pHix-up is an innovative formulation that effectively maintains optimal ruminal pH in highly productive dairy cows. Supported by our unique industrial know-how, pHix-up required 3 years of research in partnership with the French National Institute for Agronomic Research in Rennes (INRA), Inovalys laboratory and veterinarians.​

​pHix-up neutralizes 2.5 to 3 times more acid than commonly used products such as sodium bicarbonate. Its action is fast and its effect continues for 6 hours. As a result, pHix-up maintains an optimal ruminal pH between two feedings, optimizes the milk production and maintains the milk fat content in cows fed with energy-rich and consequently acidogenic diets.​

pHix-up is a natural product, obtained without any chemical transformation or additives.

In-vivo study in Spain

In June 2017, TIMAB Magnesium performed an in-vivo study in the experimental farm of BLANCA, in collaboration with Dr. Alex Bach (IRTA), to evaluate the efficiency of pHix-up in stabilizing rumen pH under induced sub-acidosis conditions.​

In this study, 30 dairy cows (Holstein) split in 3 treatments: control (no additive), pHix-up (0.5% DMI) and sodium bicarbonate (1% DMI) received a diet where the amount of barley was progressively increased to create an acidogenic diet (from +1 kg/d to +3 kg/d). ​

The study lasted 30 days. Cows in pHix-up group had a grea­ter rumen pH than control cows (with bicarbonate cows showing intermediate values) when the barley challenge was 3 kg/d. Moreover, these cows spent less time with pH<5.8 than cows in control or sodium bicarbonate group. ​

Also, cows with pHix-up had a higher dry matter intake and an increase milk production, in quantity and quality.​

pHix-up in-vivo results were published in Journal of Dairy Science.

Journal of Dairy Science

Securing dairy cows grazing season in spring with pHix-up


In spring, a metabolic disease risk appears: grass tetany (or hypomagnesemia). At this time, the young grass at pasture is rich in soluble nitrogen, fermentable carbohydrates and lower in cellulose. In addition, the magnesium to potassium ratio (Mg2+/K+) is low, which can cause a decrease in blood magnesium rate of animals, causing the grass tetany. ​

​During the same period presence of fermentable carbohydrates, associated with a low cellulose proportion in the ingested young grass, leads to a vast increase in the production of volatile fatty acids in the rumen. The accumulation of these compounds causes a pH acidification, this induces a decrease in animal food intake, milk production and milk fat content. ​

pHix-up, in additition to this effect in maintaining an optimum ruminal pH,  contains 48.5% highly available magnesium. So it also provides an adequate supplementation during the grass tetany risk period.​